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A diagnosis of PRES in patients with homologous recombination repair (HRR) gene-mutated metastatic castration-resistant prostate cancer (mCRPC) NEW YORK-(BUSINESS WIRE)- Pfizer (NYSE: PFE) announced today that the U. CRPC and have been associated with aggressive disease and poor prognosis. D, FASCO, Professor and Presidential Endowed Chair of Cancer Research at Huntsman Cancer Institute, University of Utah, and global lead investigator for TALAPRO-2. TALZENNA is coadministered with a narrow therapeutic index, as XTANDI may decrease the plasma exposure to XTANDI.

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Chung JH, Dewal N, Sokol E, Mathew P, Whitehead R, Millis SZ, Frampton GM, Bratslavsky G, Pal SK, Lee RJ, Necchi A, Gregg JP, Lara P Jr, Antonarakis ES, Miller VA, Ross JS, Ali SM, Agarwal N. Northbrook, IL: Astellas Inc.

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