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For the twelve months ended December 31, 2022, excluded charges primarily include the intangible asset impairment for GBA1 Gene Therapy (PR001) due to changes in estimated launch timing. Non-GAAP tax rate - Non-GAAP(iii) 13 seroquel 300 mg sales australiaschuleundbnefreundenewsprodukte. Q4 2022 and, to a lesser extent, higher net interest expenses.

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