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acetazolamide (Diamox);
cimetidine (Tagamet), ranitidine (Zantac);
morphine (MS Contin, Kadian, Oramorph);
ranitidine (Zantac);
topiramate (Topamax);
trimethoprim (Proloprim, Primsol, Bactrim, Cotrim, Septra) or vancomycin (Vancocin, Lyphocin);
glipizide (Glucotrol, Metaglip), glimepiride (Amaryl, Avandaryl, Duetact), glyburide (DiaBeta, Micronase, Glucovance); or
heart or blood pressure medications such as amiloride (Midamor), digoxin (Lanoxin), furosemide (Lasix), nifedipine (Nifedical, Procardia), procainamide (Procan, Pronestyl, Procanbid), quinidine (Quin-G), triamterene (Dyrenium).

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isoniazid;
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niacin (Advicor, Niaspan, Niacor, Simcor, Slo-Niacin, and others);
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seizure medicines (Dilantin and others); or
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These lists are not complete and there are many other medicines that can increase or decrease the effects of Janumet on lowering your blood sugar. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

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