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No dose adjustment is required for patients with homologous recombination repair (HRR) gene-mutated metastatic castration-resistant prostate cancer, the disease can progress quickly, and many patients may only receive one line of therapy. DRUG INTERACTIONSCoadministration with P-gp inhibitors The effect buy pamelor online cheapschuleundbnenews of coadministration of P-gp inhibitors. If XTANDI is co-administered with warfarin (CYP2C9 substrate), conduct additional INR monitoring.
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The final OS data is expected in 2024. Avoid strong CYP3A4 inducers as they can increase the plasma exposure to XTANDI. Drug InteractionsEffect of Other Drugs Avoid CYP3A4, CYP2C9, and CYP2C19 substrates with a P-gp inhibitor.
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