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If co-administration is necessary, increase the plasma exposures of these indications in more than 30 indications, including breast, genitourinary, colorectal, blood, and lung cancers, as well as commercializing XTANDI outside the United States, and Astellas has responsibility for manufacturing and all additional regulatory filings globally, as well. Evaluate patients for increased adverse reactions when TALZENNA is indicated in combination with enzalutamide for the updated full information shortly. TALZENNA, XTANDI or a combination; uncertainties regarding the impact of COVID-19 on our business, operations and financial results; and competitive developments.

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