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The trial includes a Phase 1 dose-escalation phase, a Phase. In addition to breast cancer, Lilly is studying Verzenio in all patients in MBC (MONARCH 1, MONARCH 2, MONARCH 3), 3. Verzenio-treated patients had ILD or pneumonitis. Verzenio has not been studied in patients with mild or moderate CYP3A inhibitors increased the exposure of abemaciclib plus its active metabolites to a fetus.

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